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S-Adenosylmethionine

Introduction

Applications

Functions

the therapy of depression

Possess anti-inflammatory and tissue-healing

Improve mood in those with Parkinson's disease.

S-Adenosylmethionine

Introduction

S-Adenosylmethionine is made from the amino acid methionine and ATP. It is is a methyl donor involved in the making of dozens of important compounds in the body. SAM-e has been available by prescription in Europe for many years as an antidepressant but has been available over the counter in the US only since about 1996. Dr. Ascanio Polimeni, a physician in Rome, Italy, says, "S-Adenosylmethionine is a wonderful supplement. Some doctors prescribe SAM-e in Europe for the therapy for many conditions, including depression, chronic fatigue syndrome, and fibromyalgia."

Unlike other methyl donors where the research is scarce, there have been a number of studies with S-Adenosylmethionine. These studies have shown that SAM-e influences brain chemicals by helping to convert norepinephrine to epinephrine and serotonin to melatonin, helping make creatine, an important energy reservoir in muscle tissue, and helping the preservation of glutathione, an important antioxidant. Furthermore, SAM-e is involved in the formation of myelin, the white sheath that surrounds nerve cells and it can improve brain cell membrane fluidity, thus potentially enhancing the function of receptors.

Functions

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