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Grape seed given hypertension thumbs up

09.30.2013

Researchers say that new grape seed procyanidins (GSP) product – now only using water as extraction solvent – is effective in blood pressure management when coupled with lifestyle factors.

Study details

The researchers at Gabriele D’Annunzio University Chieti-Pescara in Italy used this product in their four month trial in which 119 otherwise healthy pre- and mildly hypertensive participants were split across three groups.

This trial was longer than two previous studies which cited GSP’s potential for hypertension reduction. These studies took place over a four week period, an important distinction since this latest study saw that blood pressure normalisation started to be higher in the GSP supplementation groups around the fourth week of the trials.

Group 1 (37 subjects) and Group 2 (35 subjects) supplemented a non-drug management plan at two different daily dosages (300 mg/day for Group 1 and 150 mg/day for Group 2), while in the control Group 3 (47 subjects) only the management plan was implemented.

The nondrug intervention comprised of adjustments to diet (reduction in salt, alcohol and caffeinated drinks) and lifestyle (regular exercise, getting more sleep and relaxation time and reduction of smoke). No other nutritional elements, vitamins or drugs were used in the observation period.

Dr. Gianni Belcaro, who headed the Gabriele D’Annunzio University Chieti-Pescara study, said: “Taken together, our data suggest that GSPs, are worth considering to complement dietary and lifestyle changes associated to the maintenance of a healthy blood pressure status, with beneficial cardiovascular effect”.


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