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Vitamin E forms show cholesterol-lowering potential

12.20.2018

Vitamin E forms show cholesterol-lowering potential

Post a comment By Shane Starling, 08-Nov-2011

Related topics: Research, Vitamins & premixes, Cardiovascular health Alpha and gamma forms of vitamin E lower cholesterol levels in rabbits but the delta form the vitamin do not, researchers have found. The alpha and gamma tocotrienol forms showed positive effects on cholesterol levels with rabbits fed a cholesterol diet for 60 days, supplemented with the different vitamin E forms for the last 30 days. “The results of the present study demonstrate that the two isomers of tocotrienols [alpha and gamma], render the hypercholesterolemic hearts resistant to ischemic reperfusion injury by lowering several hypercholesterolemic proteins…” the researchers said. They added: “Left ventricular function including aortic flow and developed pressure exhibited significantly improved recovery with tocotrienol [alpha and gamma], but not with tocotrienol [delta].” The researchers detected a difference between female and male responses to the introduced vitamin E forms. “The major findings of this study are that [alpha and [gamma] isomers, but not [delata] isomer improved the left ventricular function and reduced myocardial infarct size in the hearts of hypercholesteromic rabbits,” they said. “Interestingly, the female rabbit hearts were more resistant to ischemic reperfusion injury compared to male hearts. Although tocotrienol isomers effectively reduced the serum cholesterol in the hypercholesteromic rabbits, there was no difference between the male and female rabbits. Expression of cholesterol-related protein profiles revealed differential effects of tocotrienol isomers.”


Source:

Molecular Cell Biology

DOI 10.1007/s11010-011-1041-9

‘Tocotrienols confer resistance to ischemia in hypercholesterolemic hearts:insight with genomics’

Authors: Somak Das et al This content is copyright protected However, if you would like to share the information in this article, you may use the headline, summary and link below:

Vitamin E forms show cholesterol-lowering potential: Rabbit study

Alpha and gamma forms of vitamin E lower cholesterol levels in rabbits but the delta form the vitamin do not, researchers have found.

http://www.nutraingredients.com/Research/Vitamin-E-forms-show-cholesterol-lowering-potential-Rabbit-study.



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