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Quercetin shows promise against Metabolic

11.20.2012

Quercetin, a compound found in fruit and vegetables, may protect against the detrimental effects of a

high fat diet, including the build-up of abdominal fat, suggests a new studying.

The effects of the flavonol are most likely related to its activity against oxidative stress and inflammation,

“Quercetin supplementation attenuated the changes in expression of markers for oxidative stress and inflammation

in the liver and the heart,” wrote researchers.

“Thus, quercetin can be considered as a nutraceutical with potential [against] metabolic syndrome; clinical trials of

this relatively safe natural compound should be undertaken.”

Metabolic syndrome (MetS) is a condition characterised by central obesity, hypertension, and disturbed glucose and

insulin metabolism. The syndrome has been linked to increased risks of both type-2 diabetes and cardiovascular

disease (CVD).

Fifteen per cent of adult Europeans are estimated to be affected by MetS, while the US statistic is estimated to be a

whopping 32 percent. Obesity is established to be the main risk factor for MetS.

The compound

Quercetin is an antioxidant flavonoid found in fruits and vegetables. Potential health benefits include lowering of

inflammatory markers, cholesterol reduction, and improving blood pressure.

However, many of these potential benefits are the result of in vitro or animal studies and data from human studies

is rare.

One such human study by researchers did indicate that a daily 730 milligram

supplement of quercetin led to significant reductions in blood pressure.


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